The United Nations Office for Disarmament Affairs is structured in five branches:

CD Secretariat & Conference Support Branch (Geneva)

The CD Secretariat and Conference Support Branch (Geneva) provides organizational and substantive servicing to the Conference on Disarmament (CD), the single multilateral disarmament negotiating forum of the international community, and its Ad hoc Committees.

Weapons of Mass Destruction (WMD) Branch

WMD Branch provides substantive support in the area of the disarmament of weapons of mass destruction (nuclear, chemical and biological weapons). It supports and participates in multilateral efforts to strengthen the non-proliferation of WMD and in this connection cooperates with the relevant intergovernmental organizations and specialized agencies of the United Nations system, in particular the IAEA, the OPCW and the CTBTO PrepCom.

Conventional Arms Branch (CAB)

CAB focuses its efforts on all weapons not considered WMD, including small arms and light weapons (SALW). It is responsible for substantive conference support on the UN Programme of Action on small arms, the Arms Trade Treaty process, and the UN transparency registers. CAB chairs the UN-internal coordination mechanism on small arms (CASA).

Regional Disarmament Branch (RDB)

RDB provides substantive support, including advisory services, to Member States, regional and subregional organizations on disarmament measures and related security matters. RDB oversees and coordinates the activities of the three Regional Centres for Peace and Disarmament: Africa, Asia and the Pacific, and Latin America and the Caribbean .

Information and Outreach Branch (IOB)

IOB organizes a wide variety of special events and programmes in the field of disarmament, produces UNODA publications (such as the Disarmament Yearbook and ODA Occasional Papers), updates content and design of the UNODA website, and maintains databases for specialized areas (Status and Texts of Disarmament Treaties, General Assembly Resolutions and Decisions and UNODA Documents Library).

UNODA Office in Vienna

UNODA has established an office at the Vienna International Centre with administrative and logistical support provided by UNOV. This office was established to facilitate closer cooperation and effective interaction in all areas of disarmament, non-proliferation and arms control with UNOV, and with Vienna-based organizations and related specialized agencies, such as the IAEA , the CTBTO and the UNODC, as well as with other relevant regional intergovernmental organizations, such as the OSCE.